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- Why the opioid problem keeps showing up after surgery
- ERAS in plain English (no, it’s not a new yoga class)
- The ERAS “secret sauce”: multimodal, opioid-sparing pain control
- 1) Start before the first incision: education and expectation setting
- 2) Use non-opioid medications on purpose (not as an afterthought)
- 3) Regional anesthesia: turning down the “pain volume” at the source
- 4) ERAS reduces “pain multipliers” like nausea, ileus, and grogginess
- 5) Discharge opioid stewardship: fewer pills, clearer instructions
- What the evidence says: ERAS can reduce opioids and improve recovery
- Specific examples: what ERAS looks like in real surgical settings
- ERAS doesn’t mean “opioid-free for everyone”
- How hospitals implement ERAS without losing their minds
- What patients can do: questions that lead to fewer opioids
- Bottom line: ERAS helps fix the system, not just the symptoms
- Experiences that bring ERAS to life (what it feels like in practice)
If you’ve ever watched someone wake up after surgery and thought, “Wow, modern medicine is amazing,” you’re right.
If you’ve ever watched the same person go home with a bottle of opioids they didn’t really need (or didn’t know how to taper),
you’re also right. Surgery can be a “first contact” moment with opioidsespecially for opioid-naïve patientsbecause post-op pain is real,
and traditional pain plans have often leaned on “just add opioids” like it’s a casserole recipe.
Enhanced Recovery After Surgery (ERAS) changes that script. It’s not a magic wand and it’s definitely not a “tough it out” program.
ERAS is a practical, evidence-based, team approach that reduces surgical stress, speeds up recovery, andcruciallyuses
multimodal, opioid-sparing pain control so opioids become a backup tool, not the main character.
When done well, ERAS helps patients hurt less, move sooner, leave the hospital earlier, and rely less on opioids during and after recovery.
Why the opioid problem keeps showing up after surgery
The U.S. opioid crisis has many causes, but postoperative prescribing is one of the places where “normal care” can accidentally create
long-term risk. Research has shown that new persistent opioid use after surgery happens often enough to mattereven after procedures
where pain should fade as healing progresses. And prescribing practices can vary widely, which is a polite way of saying the same operation might
come with “six pills” in one place and “sixty” in another.
A few things make post-op opioid risk sneakier than people expect:
- Leftover pills can sit in medicine cabinets like tiny time bombs for misuse or diversion.
- Side effects (nausea, constipation, sedation) can slow recovery and make patients feel worse overall.
- Some patients are more vulnerable to persistent useespecially those with certain mental health conditions, chronic pain histories, or tobacco use.
- People are often not taught how to taper, what “normal pain” feels like, or which non-opioid options actually work.
In other words: the opioid issue isn’t just about “bad choices.” It’s also about systems that accidentally make risky choices easier than safe ones.
ERAS is a system fix.
ERAS in plain English (no, it’s not a new yoga class)
Enhanced Recovery After Surgery is a structured pathway covering before, during, and after surgery.
It coordinates surgeons, anesthesiologists, nurses, pharmacists, physical therapists, and patients around one goal:
better recovery with fewer complications and fewer “avoidable” setbacks (like ileus, severe nausea, deconditioning, or uncontrolled pain).
ERAS programs vary by procedurecolorectal surgery and joint replacement don’t require the exact same playbookbut the principles are consistent:
- Set expectations early (education, pain goals, realistic milestones).
- Reduce surgical stress (smart fluids, temperature control, minimizing unnecessary tubes/drains).
- Prevent problems proactively (nausea control, early nutrition, early mobility).
- Use multimodal analgesia (multiple non-opioid tools that add up to strong pain control).
- Prescribe opioids thoughtfully (lowest effective dose, shortest necessary duration, clear taper plan).
The ERAS “secret sauce”: multimodal, opioid-sparing pain control
ERAS doesn’t pretend pain is optional. It just treats pain like a real physiologic problemwith more than one solution.
Multimodal analgesia combines medications and techniques that work through different pathways so you get better relief with less opioid exposure.
1) Start before the first incision: education and expectation setting
Pre-op teaching might sound like paperwork with better branding, but it’s powerful.
Patients do better when they know what’s normal, what’s not, and how pain will be managed.
ERAS education often includes:
- What pain levels to expect (and what “acceptable control” means)
- How scheduled non-opioids work (and why waiting until pain is severe is a losing strategy)
- How to use “rescue” opioids sparingly and safely
- How tapering works and when to call for help
ERAS also emphasizes risk screeningfor example, identifying patients already taking opioids, those with sleep apnea, or those at higher risk
of postoperative nausea/vomiting. That allows the team to tailor an opioid-sparing plan instead of improvising at 2 a.m.
2) Use non-opioid medications on purpose (not as an afterthought)
In many ERAS pathways, non-opioids are scheduledmeaning they’re given regularly, not only when pain becomes unbearable.
Common building blocks include:
- Acetaminophen (often scheduled)
- NSAIDs or COX-2 inhibitors when appropriate (careful in patients with kidney risk, bleeding risk, or certain surgeries)
- Regional anesthesia and local anesthetics (nerve blocks, spinal/epidural strategies in selected cases, or surgical-site infiltration)
- Adjuncts in some protocols (e.g., gabapentinoids, ketamine, lidocaine infusions), depending on patient factors and procedure
The point is not to throw the whole pharmacy at someone. The point is to select a few tools that
work together so opioids become optional rather than inevitable.
3) Regional anesthesia: turning down the “pain volume” at the source
Regional anesthesia can be a game-changer: nerve blocks and local anesthetic techniques reduce pain signals before they snowball.
In orthopedic surgery, for example, regional approaches can help patients participate in early physical therapy with less reliance on opioids.
For abdominal procedures, certain plane blocks can reduce abdominal wall pain and improve comfort when coughing, breathing deeply, or getting out of bed.
Think of it like noise-canceling headphones for your nervous system: you still hear the world, but it’s not screaming at you.
4) ERAS reduces “pain multipliers” like nausea, ileus, and grogginess
Opioids can worsen nausea and constipation, and they can slow gut functionespecially after abdominal surgery.
ERAS tackles those complications directly with:
- Better anti-nausea plans
- Earlier nutrition (when appropriate) to help the gut wake up
- Early mobilization (movement helps everything, including pain perception)
- Less routine use of tubes and drains when not needed
When patients feel less nauseated, less bloated, and less sedated, they often need fewer opioids because they’re not fighting three problems at once.
5) Discharge opioid stewardship: fewer pills, clearer instructions
A sneaky part of the opioid problem is what happens after the hospital. ERAS programs increasingly focus on discharge prescriptions:
prescribing smaller quantities, giving clear tapering steps, and emphasizing non-opioid options first.
Some perioperative quality groups also highlight the importance of returning to (or below) pre-op opioid doses within a reasonable timeframe after major surgery
when clinically appropriatebecause “indefinite opioids” should not be the default recovery plan.
What the evidence says: ERAS can reduce opioids and improve recovery
ERAS isn’t trendy because it sounds nice on a hospital brochure. It’s supported by a growing body of research showing benefits like:
- Reduced opioid consumption (in-hospital and sometimes after discharge)
- Better pain control through multimodal strategies
- Shorter length of stay for many procedures
- Fewer complications and improved patient experience in multiple surgical specialties
Reviews of ERAS programs and pain management within ERAS frequently emphasize the same theme:
multimodal, opioid-sparing analgesia improves pain outcomes while reducing opioid exposurewithout asking patients to suffer.
Specific examples: what ERAS looks like in real surgical settings
Colorectal surgery: protecting the gut and the patient
Colorectal procedures are famous for postoperative ileus (the gut “going on strike”).
ERAS pathways often prioritize opioid-sparing strategies, early feeding protocols when safe, and mobility.
When opioid use drops, constipation and nausea often improvemaking it easier to eat, move, and go home sooner.
Orthopedic surgery: pain control that supports movement
Joint replacement recovery depends on early mobility and physical therapy.
ERAS approaches in orthopedics often emphasize regional anesthesia, scheduled non-opioids, and functional goals (walk, stairs, exercises),
so pain control supports recovery rather than sedating it.
Thoracic and cardiac surgery: comfort without the opioid fog
In chest surgery, deep breathing and coughing are essential to prevent pulmonary complications.
Opioid-sparing strategies plus regional techniques can help patients breathe and move comfortablywithout trading pain for “opioid fog.”
Some newer ERAS implementations in cardiac surgery have reported reduced opioid use alongside faster functional recovery steps like earlier mobilization.
ERAS doesn’t mean “opioid-free for everyone”
Some surgeries and some patients still require opioidssometimes absolutely.
ERAS is not a purity test. It’s a safety-and-recovery strategy.
The goal is the right pain control with the least risk.
That also means ERAS must be individualized. For example:
- NSAIDs may be limited for certain kidney risks, bleeding risks, or procedure types.
- Some patients can’t tolerate certain adjuncts due to side effects or interactions.
- Patients on chronic opioids need specialized planning (often with pain specialists) to avoid withdrawal and manage tolerance.
In practice, ERAS is “standardized where it should be, customized where it must be.”
How hospitals implement ERAS without losing their minds
The best ERAS programs behave like good restaurants: consistent menu, great teamwork, and nobody waiting until the last second to decide what’s for dinner.
Implementation often includes:
- Standard order sets for multimodal pain management
- Team protocols spanning pre-op clinic to discharge planning
- Data tracking (opioid use, pain scores, nausea, length of stay, readmissions)
- Education for staff and patients
- Feedback loops to improve adherence and outcomes
National toolkits aimed at improving surgical recovery have also emphasized multidisciplinary approaches and practical resources to help hospitals adopt
enhanced recovery practices at scale.
What patients can do: questions that lead to fewer opioids
Even the best protocol works better when patients know what to ask. If you’re preparing for surgery, consider asking:
- “Do you use an ERAS pathway for this surgery?”
- “What is the plan for multimodal pain control?” (Ask about non-opioids and regional anesthesia options.)
- “If I need opioids, how many will I getand how do I taper?”
- “What side effects should I expect and how do we prevent them?” (Nausea, constipation, sleepiness.)
- “How do I dispose of leftover pills safely?”
This isn’t being “difficult.” This is being prepared. Surgery is stressful; your plan shouldn’t be.
Bottom line: ERAS helps fix the system, not just the symptoms
The opioid crisis is complicated, but the postoperative slice of it is something healthcare teams can influence immediately.
ERAS helps by reducing the need for opioids through better pain science, better teamwork, and better patient preparation.
It replaces “opioids first” with “recovery first,” whichironicallyoften reduces pain too.
If you want a future where fewer people meet opioids in a hospital and keep seeing them long after the incision heals,
ERAS is one of the most practical, evidence-based ways to get there.
Medical note: This article is for general educational purposes and isn’t medical advice.
ERAS elements vary by surgery and patient risk. Always discuss pain control and medication choices with your surgical and anesthesia team.
Experiences that bring ERAS to life (what it feels like in practice)
Let’s make this real with a few common ERAS-style experiencescomposites based on how enhanced recovery pathways are typically used in U.S. hospitals.
No dramatic TV monitors, no last-minute hero speechesjust lots of small, smart decisions that add up to fewer opioids and a smoother recovery.
Experience #1: “I woke up… and I wasn’t miserable”
A patient heading into abdominal surgery often expects two things: pain and nausea. In a traditional approach, opioids may blunt pain,
but then nausea roars in, the gut slows down, and the patient feels like they got hit by a truck that also stole their appetite.
With ERAS, the day starts differently. Before surgery, the patient is told exactly how pain will be managed: scheduled non-opioids,
a regional block or local anesthetic technique if appropriate, and opioids only if needed as “rescue.”
Post-op, the patient wakes up still sorebecause surgery happenedbut not spiraling. The pain is more “tight and tender”
than “full-body alarm.” Nurses push early nausea prevention, and instead of waiting for a pain crisis,
the patient receives non-opioid meds on schedule. When the patient asks, “Am I allowed to drink water?” the answer is “Yes, let’s start.”
When the patient asks, “Am I allowed to sit up?” the answer is “Yes, and we’ll help.”
That early momentum matters: less fear, less guarding, less immobilityand often less opioid demand.
Experience #2: “Physical therapy didn’t feel like punishment”
In orthopedic recovery, the difference between “I can’t move” and “I can try” often comes down to pain strategy.
ERAS-style ortho care commonly pairs regional anesthesia with non-opioids so the first PT session feels doable.
Patients often describe the block as giving them a “window” where movement feels possible.
And when the block fades, they aren’t abandoned; the schedule of non-opioids is already in place, and opioidsif usedare used carefully,
because the goal isn’t sedation, it’s function.
The funniest part is how normal the win feels. Nobody stands and applauds when you walk to the bathroom.
But when you can walk to the bathroom on post-op day one with controlled pain and a clear head, you’re stacking the odds in your favor:
fewer complications, stronger confidence, and usually a smaller opioid footprint.
Experience #3: “Going home with a plan, not a mystery bottle”
Discharge is where opioid problems can quietly begin. ERAS-informed discharge often feels more structured:
a smaller opioid prescription (or none at all for some procedures), written tapering instructions, and a clear message:
“Use non-opioids first, use opioids only for breakthrough pain, and here’s how to step down.”
Patients frequently say the clarity reduces anxiety. Instead of guessing, they know what to do on day three when pain flares at night.
They know constipation prevention isn’t optional. They know when to call. And they know leftover pills are not souvenirs.
That’s how ERAS helps “solve” opioid problems in the real world: not by pretending pain doesn’t exist,
but by making the safe choice the easy, obvious choice.
Experience #4: The clinician perspectiveless chasing, more preventing
Ask a nurse or anesthesiologist what ERAS changes, and you’ll often hear a version of:
“We spend less time reacting to emergencies we accidentally created.”
When multimodal analgesia is planned, nausea prevention is proactive, and mobility is expected,
teams aren’t stuck in the cycle of “opioids cause nausea, nausea prevents eating, not eating slows recovery, slow recovery increases pain.”
Instead, they’re preventing that loopso the patient’s whole day feels more stable.
ERAS isn’t flashy. It’s simply what happens when a hospital decides that recovery is a process worth designing.
And in a country still wrestling with opioid harm, that design choice can save a lot of troubleone surgery at a time.
